WT1 protein-specific T-cell therapy - Atara Biotherapeutics/Memorial Sloan-Kettering Cancer Center

Drug Profile

WT1 protein-specific T-cell therapy - Atara Biotherapeutics/Memorial Sloan-Kettering Cancer Center

Alternative Names: ATA 520; WT1 peptide-specific T-cells - Atara/MSKCC; WT1-CTL - Atara/MSKCC; WT1-sensitised T cells - Atara/MSKCC; WT1-targeted T cells - Atara/MSKCC

Latest Information Update: 23 Feb 2018

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At a glance

  • Originator Memorial Sloan-Kettering Cancer Center
  • Developer Atara Biotherapeutics; Memorial Sloan-Kettering Cancer Center
  • Class Gene therapies; Immunotherapies; T lymphocyte cell therapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Leukaemia; Multiple myeloma

Most Recent Events

  • 23 Feb 2018 WT1 protein-specific T-cell therapy is still at phase I development stage for Leukaemia and Multiple myeloma in USA (IV) (Atara Biotherapeutics pipeline, February 2018)
  • 04 Nov 2017 No recent reports of development identified for phase-I development in Multiple-myeloma(Refractory metastatic disease) in USA (IV, Infusion)
  • 15 Mar 2017 Atara Biotherapeutics plans a phase I/II clinical trial in patients with Hematologic malignancies in 2018 (Atara Biotherapeutics Form 10-K, December 2016)
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