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JNJ 54175446

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Drug Profile

JNJ 54175446

Alternative Names: JNJ-54175446; JNJ-5446

Latest Information Update: 25 Jul 2022

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At a glance

  • Originator Janssen-Cilag
  • Class Antidepressants; Azoles; Phenols; Pyridines; Pyrimidines
  • Mechanism of Action Purinergic P2X7 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Major depressive disorder

Most Recent Events

  • 25 Jul 2022 JNJ 54175446 is still in phase II trials for Major depressive disorder (Adjunctive treatment) in United Kingdom (PO) (NCT04116606) (ISRCTN44411633) (EudraCT2018-001884-21)
  • 05 Nov 2020 Janssen-Cilag reinitiates phase II trial in Major depressive disorder in United Kingdom (ISRCTN44411633) (NCT04116606)
  • 28 Apr 2020 No recent reports of development identified for phase-I development in Major depressive disorder(In volunteers) in Belgium (PO, Capsule)

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