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B 244

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Drug Profile

B 244

Alternative Names: AOB 101; AOB 102; AOB 103; AOB 201; AOB 202; AOB 203; B244; Nitrosomonas eutropha D23

Latest Information Update: 14 Mar 2024

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At a glance

  • Originator AOBiome
  • Developer AOBiome; Novella Clinical
  • Class Anti-inflammatories; Antiacnes; Antiallergics; Antibacterials; Antihypertensives; Antimigraines; Antipruritics; Bacteria; Skin disorder therapies
  • Mechanism of Action Bacteria replacements; Nitric oxide donors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II/III Acne vulgaris
  • Phase II Atopic dermatitis; Hypertension; Pruritus; Rosacea
  • Phase I/II Allergic rhinitis; Eczema
  • No development reported Migraine; Skin disorders; Staphylococcal infections

Most Recent Events

  • 05 Jan 2024 AoBiome Therapeutics plans phase III trials in Atopic dermatitis in the second half of 2024
  • 05 Jan 2024 Maruho and AOB Pharma agree to co-develop B 244 in Japan for Atopic Dermatitis and Pruritus
  • 06 Apr 2023 AOBiome Therapeutics has patent protection for composition of matter patent for proprietary strain of Ammonia Oxidizing Bacteria (AOB) in Europe and Hong Kong

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