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Cycloserine/lurasidone - NRx Pharmaceuticals

Drug Profile

Cycloserine/lurasidone - NRx Pharmaceuticals

Alternative Names: Cyclurad; Lurasidone/cycloserine; NRX-101

Latest Information Update: 13 Sep 2022

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At a glance

  • Originator NeuroRX
  • Developer NeuroRX; NRx Pharmaceuticals
  • Class Antidepressants; Antituberculars; Behavioural disorder therapies; Isoindoles; Isoxazoles; Piperazines; Small molecules; Thiazoles
  • Mechanism of Action Dopamine D2 receptor antagonists; Glycine gated NMDA receptor agonists; Serotonin 2A receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase III Bipolar depression
  • Phase II Suicidal ideation

Most Recent Events

  • 08 Sep 2022 NeuroRx plans a registrational phase IIb/III trial for Bipolar Depression in the fourth quarter of 2022
  • 11 May 2022 Phase-II clinical trials in Suicidal ideation in USA (PO) (NCT03395392)
  • 11 May 2022 NeuroRx initiates enrolment in a phase II trial for Bipolar depression in USA (PO) (NCT03395392)
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