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S 81694

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Drug Profile

S 81694

Alternative Names: NMS P153; NMS-01940153; NMS-01940153E; NMS-153; S-81694

Latest Information Update: 23 Jan 2025

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At a glance

  • Originator Nerviano Medical Sciences
  • Developer Nerviano Medical Sciences; Servier
  • Class Antineoplastics; Small molecules
  • Mechanism of Action TTK protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Breast cancer; Liver cancer
  • No development reported Acute myeloid leukaemia; Precursor B-cell lymphoblastic leukaemia-lymphoma; Solid tumours

Most Recent Events

  • 07 Jan 2025 Nerviano Medical Sciences plans a phase IIa trial for Liver cancer (Inoperable/unresectable, Second-line therapy or greater) in Italy and Spain (IV) (EUCT-2024-516737-12-00)
  • 28 Dec 2024 No recent reports of development identified for preclinical development in Acute-myeloid-leukaemia in France (IV)
  • 28 Dec 2024 No recent reports of development identified for preclinical development in Precursor-B-cell-lymphoblastic-leukaemia-lymphoma in France

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