Research programme: antibacterials - Entasis Therapeutics

Drug Profile

Research programme: antibacterials - Entasis Therapeutics

Alternative Names: ETX 0282; ETX 0282 CPDP; ETX 1317

Latest Information Update: 04 Jul 2017

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At a glance

  • Originator AstraZeneca
  • Developer Entasis Therapeutics
  • Class Antibacterials; Small molecules
  • Mechanism of Action Beta lactamase inhibitors; Penicillin-binding protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Gram-negative infections

Most Recent Events

  • 12 Mar 2018 Entasis Therapeutics plans a phase I trial for Gram-negative infections (In volunteers) in Australia in April 2018 (ACTRN12618000350224p)
  • 07 Jun 2017 Entasis Therapeutics and CARB-X plan a clinical trial of ETX 0282 for Gram-negative infections
  • 07 Jun 2017 Preclinical trials in Gram-negative infections (Combination therapy) in USA (PO), before June 2017
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