ABX 1431

Drug Profile

ABX 1431

Alternative Names: ABX-1431; ABX-1431 HCl

Latest Information Update: 13 Apr 2018

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At a glance

  • Originator Abide Therapeutics
  • Developer Abide Therapeutics; University of Oxford
  • Class Analgesics; Anti-inflammatories; Small molecules
  • Mechanism of Action Cannabinoid receptor agonists; Monoacylglycerol lipase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Gilles de la Tourette's syndrome; Neurological disorders; Neuropathic pain; Non-ulcer dyspepsia; Pain

Most Recent Events

  • 31 Mar 2018 Abide Therapeutics and University of Oxford completes the phase I trial in Pain in United Kingdom (PO) (NCT02929264)
  • 28 Mar 2018 Abide Therapeutics regained worldwide rights to ABX 1431 and terminates its licence with Celgene Corporation
  • 28 Nov 2017 Topline efficacy and safety data from phase Ib trial of ABX 1431 in Gilles de la Tourette's syndrome released by Abide Therapeutics
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