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Mosunetuzumab - Genentech

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Drug Profile

Mosunetuzumab - Genentech

Alternative Names: Anti-CD20/CD3 T-cell dependent bispecific antibody; BTCT 4465A; CD20-TBD; CD20xCD3 T-cell engaging bispecific antibody; Lunsumio; Lunsumio VELO; mosunetuzumab-axgb; RG7828; RO7030816

Latest Information Update: 06 Mar 2026

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At a glance

  • Originator Genentech
  • Developer Chugai Pharmaceutical; Genentech; Roche
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Cytotoxic T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Follicular lymphoma
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Follicular lymphoma
  • Preregistration Non-Hodgkin's lymphoma
  • Phase II Diffuse large B cell lymphoma; Marginal zone B-cell lymphoma; Systemic lupus erythematosus
  • Phase I/II Chronic lymphocytic leukaemia
  • No development reported B-cell lymphoma

Most Recent Events

  • 06 Mar 2026 Launched for Follicular lymphoma (Second-line therapy or greater) in Norway (SC)
  • 06 Mar 2026 Launched for Follicular lymphoma (Second-line therapy or greater) in Sweden, Spain, Singapore, Ireland, Hungary, Denmark, Portugal, Hong Kong, Finland, Czech Republic, Norway (IV)
  • 28 Feb 2026 No recent reports of development identified for phase-I development in B-cell lymphoma(Combination therapy, Late-stage disease, Second-line therapy or greater) in USA (IV)

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