Mosunetuzumab - Genentech

Drug Profile

Mosunetuzumab - Genentech

Alternative Names: Anti-CD20/CD3 monoclonal antibody; Anti-CD20/CD3 T-cell dependent bispecific antibody; BTCT 4465A; CD20-TBD; RG7828; RO7030816

Latest Information Update: 17 Oct 2018

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At a glance

  • Originator Genentech
  • Class Antineoplastics; Bispecific antibodies; Monoclonal antibodies
  • Mechanism of Action Cytotoxic T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Chronic lymphocytic leukaemia; Non-Hodgkin's lymphoma

Most Recent Events

  • 25 Sep 2018 Roche initiates enrolment in a phase I trial for Non-Hodgkin's lymphoma (Combination therapy, Monotherapy, Second line therapy or greater) in USA (IV) (NCT03671018)
  • 24 Sep 2018 Hoffmann-La Roche plans a phase Ib/II trial for Non-Hodgkin lymphoma (Combination therapy) in USA (NCT03677141)
  • 19 Sep 2018 Hoffmann-La Roche plans a phase I/II trial for Diffuse large B-cell lymphoma in October 2018 (IV) (NCT03677154)
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