RG 7828

Drug Profile

RG 7828

Alternative Names: Anti-CD20/CD3 monoclonal antibody; Anti-CD20/CD3 T-cell dependent bispecific antibody; BTCT 4465A; CD20-TBD; RG7828

Latest Information Update: 27 Feb 2018

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At a glance

  • Originator Genentech
  • Class Antineoplastics; Bispecific antibodies; Monoclonal antibodies
  • Mechanism of Action CD20 antigen inhibitors; CD3 antigen inhibitors; Cytotoxic T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Chronic lymphocytic leukaemia; Non-Hodgkin's lymphoma

Most Recent Events

  • 08 Feb 2018 Phase-I clinical trials in Non-Hodgkin's lymphoma (Second-line therapy or greater, Recurrent) in Japan (IV) (JapicCTI-183857)
  • 03 Dec 2016 Pharmacodynamics data from a preclinical study in Non-Hodgkin's lymphoma presented at the 58th Annual Meeting and Exposition of the American Society of Haematology (ASH-Hem-2016)
  • 30 Sep 2015 Phase-I clinical trials in Chronic lymphocytic leukaemia (Second-line therapy or greater) in USA (IV)
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