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Nitric oxide inhalation - Novoteris

Drug Profile

Nitric oxide inhalation - Novoteris

Alternative Names: Thiolanox

Latest Information Update: 07 Aug 2020

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At a glance

  • Originator Novoteris
  • Developer Novoteris; University of British Columbia; University of Toronto
  • Class Anti-inflammatories; Antiacnes; Antiandrogens; Antibacterials; Antifibrotics; Antifungals; Antihypertensives; Antivirals; Cardiovascular therapies; Diagnostic agents; Free radicals; Nitrogen oxides; Non-opioid analgesics; Small molecules; Vasodilators
  • Mechanism of Action Guanylate cyclase stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cystic fibrosis
  • New Molecular Entity No

Highest Development Phases

  • Phase II Cystic fibrosis; Mycobacterial infections
  • No development reported Cystic fibrosis-associated respiratory tract infections

Most Recent Events

  • 21 Jul 2020 Mallinckrodt completes a phase II trial in non-tuberculous Mycobacterium infection (Treatment-experienced) in Canada (Inhalation) (NCT03473314)
  • 01 Apr 2020 Therapeutic Products Directorate of Health Canada approves IND application for Nitric oxide inhalation (Thiolanox) in COVID-2019 infections
  • 09 Mar 2018 Phase-II clinical trials in non-tuberculous Mycobacterium infection (Treatment-experienced) in Canada (Inhalation) (NCT03473314)
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