Oleclumab - MedImmune

Drug Profile

Oleclumab - MedImmune

Alternative Names: Anti-CD73 MAb; Anti-CD73 monoclonal antibody; MEDI-9447

Latest Information Update: 13 Aug 2018

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At a glance

  • Originator MedImmune
  • Developer European Network of Gynaecological Oncological Trial Groups; MedImmune
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action 5-Nucleotidase-inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Ovarian cancer
  • Phase I/II Non-small cell lung cancer; Pancreatic cancer
  • Phase I Solid tumours

Most Recent Events

  • 13 Aug 2018 Nordic Society for Gynaecologic Oncology plans a phase trial for Ovarian cancer (Late-stage disease, Combination therapy) (NCT03267589)
  • 06 Aug 2018 AstraZeneca plans the SYNERGY phase III trial for Breast cancer (First-line therapy, Recurrent, Unresectable/Inoperable) in October 2018 (NCT03616886)
  • 02 Aug 2018 Phase-I/II clinical trials in Pancreatic cancer (First-line therapy, Combination therapy, Metastatic disease) in USA (Parenteral) (NCT03611556)
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