Rosmantuzumab - OncoMed Pharmaceuticals

Drug Profile

Rosmantuzumab - OncoMed Pharmaceuticals

Alternative Names: Anti-RSPO3 antibody – Oncomed; Anti-RSPO3 – Oncomed; OMP-131R10; Rosmantuzumab

Latest Information Update: 09 Jan 2018

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At a glance

  • Originator OncoMed Pharmaceuticals
  • Class Antibodies; Antineoplastics; Monoclonal antibodies
  • Mechanism of Action RSPO3 protein inhibitors; Stem cell modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Colorectal cancer; Solid tumours

Most Recent Events

  • 04 Jan 2018 OncoMed Pharmaceuticals completes enrolment in its phase Ia/b trial for Colorectal cancer and Solid tumours in USA (IV) (NCT02482441)
  • 05 Apr 2017 Pharmacodynamics data from a preclinical trial in Colorectal cancer presented at the American Association for Cancer Research Annual Meeting (AACR-2017)
  • 29 Nov 2016 Interim safety, efficacy and pharmacokinetics results presented at the 28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics (EORTC-NCI-AACR-2016)
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