FLX 787

Drug Profile

FLX 787

Alternative Names: FLX-787-ODT; FLX787

Latest Information Update: 29 Mar 2018

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At a glance

  • Originator Flex Pharma
  • Class Small molecules
  • Mechanism of Action TRPA1 protein stimulants; TRPV1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Amyotrophic lateral sclerosis; Charcot-Marie-Tooth disease; Multiple sclerosis
  • Phase I Motor neuron disease
  • Preclinical Neuromuscular disorders

Most Recent Events

  • 26 Mar 2018 Adverse events and therapeutic trials data from a phase II trial in Multiple sclerosis released by Flex Pharma
  • 22 Jan 2018 Flex Pharma initiates enrolment in a phase I/II trial for Amyotrophic lateral sclerosis in USA (NCT03334786)
  • 22 Jan 2018 Flex Pharma withdraws phase I/II trial in Amyotrophic lateral sclerosis prior to enrolment, in USA (NCT03338114)
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