MSB 0011359C

Drug Profile

MSB 0011359C

Alternative Names: M-7824; MSB0011359C

Latest Information Update: 13 Jul 2018

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At a glance

  • Originator EMD Serono
  • Developer EMD Serono; M. D. Anderson Cancer Center; National Cancer Institute (USA)
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies; Recombinant fusion proteins
  • Mechanism of Action Programmed cell death-1 ligand-1inhibitors; Transforming growth factor beta inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Prostate cancer; Solid tumours
  • Phase I/II Colorectal cancer; Pancreatic cancer
  • Phase I Breast cancer

Most Recent Events

  • 13 Jun 2018 National Cancer Institute plans a phase I/II trial for Small Cell Lung Cancers (Second-line therapy or greater) in USA, in July 2018 , (NCT03554473)
  • 04 Jun 2018 Adverse events data from a phase I trial in Solid tumours presented at the 54th Annual Meeting of the American Society of Clinical Oncology (ASCO-2018)
  • 04 Jun 2018 Updated efficacy and adverse events data from a phase II trial in Solid tumours presented at the 54th Annual Meeting of the American Society of Clinical Oncology (ASCO-2018)
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