Tropifexor - Novartis

Drug Profile

Tropifexor - Novartis

Alternative Names: LJN452

Latest Information Update: 14 Jun 2018

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At a glance

  • Originator Novartis
  • Class Anti-inflammatories; Antifibrotics; Benzothiazoles; Oxazoles
  • Mechanism of Action Farnesoid X-activated receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Non-alcoholic steatohepatitis; Primary bile acid malabsorption; Primary biliary cirrhosis

Most Recent Events

  • 07 May 2018 Novartis Pharmaceuticals plans the TANDEM phase II trial for Non-alcoholic Steatohepatitis in July 2018 , (NCT03517540)
  • 29 Jan 2018 Chemical structure information added
  • 25 Jan 2018 Novartis Pharmaceuticals completes a phase II trial for Primary bile acid malabsorption in USA, United Kingdom and Germany (PO) (NCT02713243)
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