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Lipoic acid choline ester - Novartis

Drug Profile

Lipoic acid choline ester - Novartis

Alternative Names: EV-06; Lipoic acid choline ester 1.5%; Lipoic acid choline ester chloride; Thioctic acid choline ester; UNR 844; UNR844-Cl

Latest Information Update: 25 Dec 2021

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At a glance

  • Originator Encore Vision
  • Developer Novartis
  • Class Carboxylic acids; Coenzymes; Esters; Eye disorder therapies; Fatty acids; Hepatoprotectants; Quaternary ammonium compounds; Sulfhydryl compounds; Thiophenes
  • Mechanism of Action Antioxidants; Free radical scavengers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Presbyopia

Most Recent Events

  • 30 Jun 2021 Novartis initiates a phase II trial in Presbyopia in USA (Ophthalmic) (NCT04806503)
  • 06 Apr 2021 Lipoic acid choline ester is still in phase II trial for Presbyopia in USA (Ophthalmic) (Novartis pipeline, April 2021)
  • 19 Mar 2021 Novartis plans a phase II trial for Presbyopia in May 2021 (NCT04806503)
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