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Lipoic acid choline ester - Novartis

Drug Profile

Lipoic acid choline ester - Novartis

Alternative Names: EV-06; Lipoic acid choline ester 1.5%; Lipoic acid choline ester chloride; Thioctic acid choline ester; UNR 844; UNR844-Cl

Latest Information Update: 30 Jan 2023

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At a glance

  • Originator Encore Vision
  • Developer Novartis
  • Class Carboxylic acids; Coenzymes; Esters; Eye disorder therapies; Fatty acids; Hepatoprotectants; Quaternary ammonium compounds; Sulfhydryl compounds; Thiophenes
  • Mechanism of Action Antioxidants; Free radical scavengers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Presbyopia

Most Recent Events

  • 30 Jan 2023 NCT04806503; CTP-Push; Trial is already discontinued on the basis of MR hence not covered
  • 28 Nov 2022 Discontinued - Phase-II for Presbyopia in Canada, Japan, Australia, USA (Ophthalmic)
  • 14 Oct 2022 Novartis completes a phase II trial in Presbyopia in USA, Australia, Canada and Japan (Ophthalmic) (NCT04806503)

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