Lipoic acid choline ester

Drug Profile

Lipoic acid choline ester

Alternative Names: EV-06; Thioctic acid choline ester; UNR 844

Latest Information Update: 24 Mar 2018

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At a glance

  • Originator Encore Vision
  • Developer Novartis
  • Class Carboxylic acids; Coenzymes; Eye disorder therapies; Fatty acids; Thiophenes
  • Mechanism of Action Antioxidants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Presbyopia

Most Recent Events

  • 03 Apr 2017 Novartis intends to submit NDA to the US FDA for Presbyopia in 2021
  • 20 Jan 2017 Encore Vision has been acquired and merged into Novartis
  • 05 May 2016 Efficacy and adverse event data from a phase I/II trial in Presbyopia released by Encore Vision
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