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Marstacimab - Pfizer

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Drug Profile

Marstacimab - Pfizer

Alternative Names: HYMPAVZI; Hympavzi; Marstacimab-hncq - Pfizer; PF-06741086; PF-6741086

Latest Information Update: 02 Jul 2025

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At a glance

  • Originator Pfizer
  • Class Antihaemorrhagics; Coagulants; Monoclonal antibodies
  • Mechanism of Action Lipoprotein-associated coagulation inhibitor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Haemophilia B; Haemophilia A
  • New Molecular Entity Yes

Highest Development Phases

  • Registered Haemophilia A; Haemophilia B

Most Recent Events

  • 26 Jun 2025 Efficacy and adverse events data from the phase III BASIS trial in Haemophilia A and B released by Pfizer
  • 28 May 2025 Pharmacokinetics results from preclinical trial in Hemophilia A and B presented at the 126th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics (ASCPT-2025)
  • 13 May 2025 Pfizer initiates enrolment in a Hemophilia A (In Children, In Adolescents, In adults and In elderly, Treatment-experienced) (NCT06703606)

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