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Marstacimab - Pfizer

Drug Profile

Marstacimab - Pfizer

Alternative Names: HYMPAVZI; Hympavzi; Marstacimab-hncq - Pfizer; PF-06741086; PF-6741086

Latest Information Update: 02 Jul 2025

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At a glance

  • Originator Pfizer
  • Class Antihaemorrhagics; Coagulants; Monoclonal antibodies
  • Mechanism of Action Lipoprotein-associated coagulation inhibitor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Haemophilia B; Haemophilia A
  • New Molecular Entity Yes

Highest Development Phases

  • Registered Haemophilia A; Haemophilia B

Most Recent Events

  • 26 Jun 2025 Efficacy and adverse events data from the phase III BASIS trial in Haemophilia A and B released by Pfizer
  • 13 May 2025 Pfizer initiates enrolment in a Hemophilia A (In Children, In Adolescents, In adults and In elderly, Treatment-experienced) (NCT06703606)
  • 29 Apr 2025 Pfizer completes a phase-III clinical trials in Haemophilia B (In adults, In adolescents, In the elderly) in USA, Bulgaria, Canada, China, Croatia, France, Hong Kong, India, Italy, Japan, South Korea, Mexico, Oman, Russia, Saudi Arabia, Serbia, South Africa, Spain, Taiwan, Turkey and USA (SC) (NCT03938792)

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