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Fisogatinib - CStone Pharmaceuticals

Drug Profile

Fisogatinib - CStone Pharmaceuticals

Alternative Names: BLU-554; CS 3008

Latest Information Update: 24 Apr 2024

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At a glance

  • Originator Blueprint Medicines
  • Developer Blueprint Medicines; CStone Pharmaceuticals
  • Class Acrylamides; Amines; Antineoplastics; Chlorobenzenes; Pyrans; Quinazolines; Small molecules
  • Mechanism of Action Type 4 fibroblast growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Liver cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Liver cancer
  • Discontinued Cholangiocarcinoma

Most Recent Events

  • 28 Feb 2024 Blueprint Medicines Corporation completes a phase I trial in Liver cancer (Inoperable/Unresectable) the US, China, France, Germany, Hong Kong, Italy, South Korea, Singapore, Spain, Switzerland, Taiwan, the UK (PO) (NCT02508467)
  • 01 Dec 2022 Pharmacodynamics data from a phase preclinical trial in Hepatocellular carcinoma presented at the 34th EORTC-NCI-AACR Symposium on molecular targets and cancer therapeutics
  • 31 Jan 2022 Blueprint Medicines has patents pending for fisogatinib and and other FGFR4 inhibitors in USA and other countries before January 2021
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