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Deucravacitinib - Bristol-Myers Squibb

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Drug Profile

Deucravacitinib - Bristol-Myers Squibb

Alternative Names: BMS-986165; BMS-986165-01; Sotyktu

Latest Information Update: 26 Dec 2023

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At a glance

  • Originator Bristol-Myers Squibb
  • Class Amides; Aniline compounds; Anti-inflammatories; Antipsoriatics; Antirheumatics; Cyclopropanes; Ethers; Hepatoprotectants; Organic deuterium compounds; Pyridazines; Skin disorder therapies; Small molecules; Triazoles; Urologics
  • Mechanism of Action TYK2 kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Plaque psoriasis
  • Registered Erythrodermic psoriasis; Pustular psoriasis
  • Phase III Psoriasis; Psoriatic arthritis; Sjogren's syndrome; Systemic lupus erythematosus
  • Phase II Alopecia areata; Crohn's disease; Cutaneous lupus erythematosus; Discoid lupus erythematosus; Hidradenitis suppurativa; Lupus nephritis; Ulcerative colitis
  • No development reported Autoimmune disorders; Inflammatory bowel diseases

Most Recent Events

  • 26 Dec 2023 Bristol-Myers Squibb completes a phase-II clinical trials in Ulcerative colitis (Treatment-experienced, Treatment-resistant) in USA, Canada, Netherlands, Poland, Puerto Rico, United Kingdom, Australia, Germany (PO) (NCT04613518)
  • 13 Nov 2023 Phase-II clinical trials in Hidradenitis suppurativa in USA (PO) (NCT05997277)
  • 10 Nov 2023 Pooled efficacy data from POETYK PSO-1 and POETYK PSO-2 phase-II trial in Psoriatic arthritis presented at the ACR Convergence 2023 (ACR-ARP-2023)
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