CNP 520

Drug Profile

CNP 520

Alternative Names: AMG 520; CNP520

Latest Information Update: 24 Mar 2018

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At a glance

  • Originator Novartis
  • Developer Amgen; Novartis
  • Class Antidementias; Small molecules
  • Mechanism of Action Amyloid precursor protein secretase inhibitors; BACE1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Alzheimer's disease

Most Recent Events

  • 03 Aug 2017 Phase-II/III clinical trials in Alzheimer's disease in Puerto Rico, Spain (PO) (NCT03131453) (EudraCT2016-002976-28)
  • 03 Aug 2017 Novartis initiates enrolment in the Generation S2 phase-II/III trial for Alzheimer's disease in USA (PO) (NCT03131453) (EudraCT2016-002976-28)
  • 16 Jul 2017 Safety, tolerability, pharmacokinetic and pharmacodynamic data from a phase IIa trial in Alzheimer’s disease presented at the Alzheimer’s Association International Conference 2017 (AAIC 2017)
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