Drug Profile

Ropivacaine extended release - PainReform

Alternative Names: PRF 110; PRF-110-oily solution

Latest Information Update: 05 Feb 2026

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At a glance

Originator PainReform
Class Alkanes; Amides; Anilides; Local anaesthetics; Non-opioid analgesics; Piperidines; Small molecules; Xylenes
Mechanism of Action Potassium channel antagonists; Sodium channel antagonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

Highest Development Phases

Phase II Postoperative pain

Most Recent Events

05 Feb 2026 No development reported - Phase-III for Postoperative pain in USA (Parenteral)
30 Aug 2024 PainReform completes a phase-III clinical trials in Postoperative pain in USA (Parenteral) (NCT05773846)
13 Mar 2023 Phase-III clinical trials in Postoperative pain in USA (Parenteral) (NCT05773846)

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