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RG 7386

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Drug Profile

RG 7386

Alternative Names: FAP-DR5 - Roche; RG7386; RO-6874813

Latest Information Update: 02 Aug 2018

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At a glance

  • Originator Roche
  • Class Antineoplastics; Bispecific antibodies
  • Mechanism of Action Cell death stimulants; Immunomodulators; TRAIL receptor 2 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Solid tumours

Most Recent Events

  • 26 Jul 2018 Discontinued - Phase-I for Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Recurrent) in France (IV) (Roche pipeline, July 2018)
  • 26 Jul 2018 Discontinued - Phase-I for Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Recurrent) in Spain (IV) (Roche pipeline, July 2018)
  • 26 Jul 2018 Discontinued - Phase-I for Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Recurrent) in USA (IV) (Roche pipeline, July 2018)

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