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TAK 754

Drug Profile

TAK 754

Alternative Names: BAX 888; FVIII gene therapy; SHP-654; TAK-754

Latest Information Update: 30 Oct 2021

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At a glance

  • Originator Baxalta
  • Developer Takeda
  • Class Gene therapies
  • Mechanism of Action Blood coagulation factor replacements; Gene transference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Haemophilia A
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Haemophilia A

Most Recent Events

  • 08 Jan 2019 Shire has been acquired and merged into Takeda
  • 15 Feb 2018 Phase-I/II clinical trials in Haemophilia A in USA (IV) (NCT03370172)
  • 25 Oct 2017 Shire plans a phase I/II trial for Haemophilia A worldwide by end of 2017 (NCT03370172)
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