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Remdesivir - Gilead Sciences

Drug Profile

Remdesivir - Gilead Sciences

Alternative Names: Captisol-enabled remdesivir; Captisol®-enabled GS 5734; GS-5734; Redyx; VEKLURY; Veklury

Latest Information Update: 07 Feb 2024

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At a glance

  • Originator Gilead Sciences
  • Developer Capital Medical University; China-Japan Friendship Hospital; Chinese Academy of Medical Sciences; Dr Reddys Laboratories; Gilead Sciences; INSERM; National Institute of Allergy and Infectious Diseases; NeuroActiva; Roche
  • Class Adenine nucleotides; Amines; Antivirals; Esters; Furans; Nitriles; Phosphorus compounds; Pyridazines; Pyrroles; Small molecules; Triazines
  • Mechanism of Action RNA replicase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed COVID 2019 infections
  • Phase III COVID-19 pneumonia
  • Phase II Ebola virus infections
  • No development reported Neurological disorders

Most Recent Events

  • 11 Oct 2023 Efficacy data from a phase III REDPINE trial in Covid-19 infections presented at the IDWeek 2023 (IDW-2023)
  • 11 Oct 2023 Pooled adverse events data from a phase III ACTT-1 trial, phase III PINETREE trial, phase III REDPINE trial presented at the IDWeek 2023 (IDW-2023)
  • 19 Sep 2023 European Medicines Agency (EMA) grants positive opinion to extend the use of remdesivir to treat people with COVID-2019 infections (with mild to severe hepatic impairment)
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