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At a glance
Originator
Gilead Sciences
Developer
Capital Medical University; China-Japan Friendship Hospital; Chinese Academy of Medical Sciences; Dr Reddys Laboratories; Gilead Sciences; INSERM; National Institute of Allergy and Infectious Diseases; NeuroActiva; Roche
Class
Adenine nucleotides; Amines; Antivirals; Esters; Furans; Nitriles; Phosphorus compounds; Pyridazines; Pyrroles; Small molecules; Triazines
Mechanism of Action
RNA replicase inhibitors
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
No
New Molecular Entity
Yes
Highest Development Phases
Marketed
COVID 2019 infections
Phase III
COVID-19 pneumonia
Phase II
Ebola virus infections
Phase I
Neurological disorders
Most Recent Events
07 Nov 2022
NeuroRx in collaboration with National Institute of Allergy and Infectious Diseases, University of Copenhagen, Medical Research Council, Kirby Institute, National Heart, Lung, and Blood Institute, Cardiothoracic Surgical Trials Network, and Gilead Sciences completes the phase III TESICO trial for COVID-19 respiratory infection and SARS-COV-2 acute respiratory disease (Monotherapy, Combination therapy) in USA (IV) (NCT04843761)
25 Sep 2022
Pharmacokinetics data from a phase I/II CARAVAN trial in Covid-2019 infections presented at the Annual Meeting of the American College of Clinical Pharmacology (ACCP-2022)
25 Sep 2022
Pharmacokinetics data from a phase I trial in Covid-2019 infections presented at the 2022 American College of Clinical Pharmacology Annual Meeting (ACCP-2022)
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