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Potassium bicarbonate/potassium citrate - Advicenne

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Drug Profile

Potassium bicarbonate/potassium citrate - Advicenne

Alternative Names: ADV 7103; Potassium citrate monohydrated/potassium hydrogen carbonate; Potassium citrate/potassium bicarbonate; Potassium hydrogen carbonate/potassium citrate monohydrated; Potassium-bicarbonate/potassium-citrate-Advicenne; Sibnayal

Latest Information Update: 28 Jan 2026

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At a glance

  • Originator Advicenne
  • Class Alkalinising agents; Citrates; Electrolytes; Potassium compounds; Small molecules; Urologics
  • Mechanism of Action Electrolyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cystinuria; Kidney disorders
  • New Molecular Entity No
  • Available For Licensing Yes - Kidney disorders

Highest Development Phases

  • Marketed Kidney disorders
  • No development reported Cystinuria

Most Recent Events

  • 28 Jan 2026 No recent reports of development identified for phase-I development in Cystinuria in European Union (PO, Controlled release)
  • 08 Jan 2026 Advicenne withdraws the phase II/III CORAL trial in Cystinuria (In children, In adults, In adolescents, In the elderly, In infants, Treatment-experienced) in France and Belgium (PO) due to unspecified business decision/strategic reason (EudraCT2017-002067-18) (NCT04147871)
  • 18 Mar 2025 Advicenne completes a phase I trial for Healthy volunteers in France (PO) (CTIS2024-518764-13-00)

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