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Osavampator - Takeda

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Drug Profile

Osavampator - Takeda

Alternative Names: NBI 1065845; NBI-845; TAK 653

Latest Information Update: 29 Sep 2025

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At a glance

  • Originator Takeda
  • Developer Neurocrine Biosciences; Takeda
  • Class Antidepressants; Small molecules
  • Mechanism of Action AMPA receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Major depressive disorder
  • No development reported Depressive disorders

Most Recent Events

  • 22 Sep 2025 Updated adverse event data from the phase II SAVITRI study in major depressive disorder released by Neurocrine Biosciences
  • 18 Aug 2025 Neurocrine Biosciences initiates enrolment in a phase III trial for Major depressive disorder (Adjunctive treatment, Treatment- resistant) in USA (PO, Tablet) (NCT07196501)
  • 30 May 2025 Phase-III clinical trials in Major depressive disorder (Adjunctive treatment) in USA (PO) (NCT06963021)

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