Research programme: ITK inhibitors - Corvus Pharmaceuticals

Drug Profile

Research programme: ITK inhibitors - Corvus Pharmaceuticals

Alternative Names: CPI-596; CPX-016; Interleukin-2 inducible kinase inhibitor; ITK Inhibitor; T Cell Reprogramming Drug; T-Cell Reprograming Drug

Latest Information Update: 08 Feb 2018

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At a glance

  • Originator Corvus Pharmaceuticals
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Emt protein-tyrosine kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cancer

Most Recent Events

  • 08 May 2018 Corvus Pharmaceuticals intends to file an IND application for CPI 596 in late 2018
  • 08 May 2018 Corvus Pharmaceuticals plans a phase I trial for an ITK inhibitor for Cancer in USA in early 2019
  • 26 Apr 2018 Corvus Pharmaceuticals plans a phase I/Ib trial for CPX 006 as single agent and in combination with CPI 444 for Cancer (Second-line therapy or greater) in USA in the March 2018 (NCT03454451)
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