SAGE 217

Drug Profile

SAGE 217

Alternative Names: SAGE-217

Latest Information Update: 19 Jun 2018

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At a glance

  • Originator SAGE Therapeutics
  • Class Antidepressants; Antiepileptic drugs; Antiparkinsonians; Sleep disorder therapies; Small molecules
  • Mechanism of Action GABA A receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Seizures

Highest Development Phases

  • Phase II Bipolar depression; Essential tremor; Insomnia; Major depressive disorder; Parkinson's disease; Postnatal depression
  • Phase I Seizures
  • Preclinical Dyskinesias

Most Recent Events

  • 13 Jun 2018 Sage Therapeutics collaborates with Shionogi to develop and commercialise SAGE 217 for Major depressive disorder and other indications in Japan, Taiwan and South Korea
  • 13 Jun 2018 Sage Therapeutics plans phase III trial for Major depressive disorder, in 2018
  • 12 Jun 2018 Sage Therapeutics plans an open label trial for Major depressive disorders
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