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Luvadaxistat - Takeda

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Drug Profile

Luvadaxistat - Takeda

Alternative Names: NBI 1065844; TAK 831

Latest Information Update: 14 Jan 2025

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At a glance

  • Originator Takeda
  • Developer Neurocrine Biosciences; Takeda
  • Class Antipsychotics; Fluorinated hydrocarbons; Ketones; Pyridazines; Small molecules
  • Mechanism of Action D amino acid oxidase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Friedreich's ataxia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Schizophrenia
  • No development reported Ataxia
  • Discontinued Friedreich's ataxia

Most Recent Events

  • 14 Dec 2024 Takeda terminates a phase II ERUDITE trial in Schizophrenia (Adjunctive treatment) in USA, Bulgaria, Czech Republic, Serbia, Spain as the trial failed to meet the primary endpoint (PO, Tablet) (NCT05182476)
  • 12 Sep 2024 Neurocrine Biosciences plans a phase III trial for major depressive disorder
  • 07 Dec 2021 Phase-II clinical trials in Schizophrenia (Adjunctive treatment) in Serbia (PO) (NCT05182476)

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