Dihydroergotamine - Impel NeuroPharma

Drug Profile

Dihydroergotamine - Impel NeuroPharma

Alternative Names: DHE; Dihydroergotamine Mesylate; INP-104; POD-DHE

Latest Information Update: 12 Jul 2018

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At a glance

  • Originator Impel NeuroPharma
  • Class Antimigraines; Ergotamines; Mesylates; Small molecules
  • Mechanism of Action Serotonin 1B receptor agonists; Serotonin 1D receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Migraine

Most Recent Events

  • 12 Jul 2018 Chemical structure information added
  • 22 Jun 2018 Impel NeuroPharma plans a pivotal phase III trial for Migraine in USA in the second half of 2018 (Intranasal) (NCT03557333)
  • 22 Jun 2018 US FDA approves IND application for a phase III trial of dihydroergotamine in Migraine
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