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Zervimesine - Cognition Therapeutics

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Drug Profile

Zervimesine - Cognition Therapeutics

Alternative Names: CT-1812; Elayta

Latest Information Update: 08 Apr 2026

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At a glance

  • Originator Cognition Therapeutics
  • Developer Alzheimers Clinical Trials Consortium; Cognition Therapeutics
  • Class Antidementias; Antiparkinsonians; Eye disorder therapies; Isoindoles; Neuroprotectants; Nootropics; Phenols; Small molecules; Sulfones
  • Mechanism of Action Sigma-2 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Alzheimer's disease; Dry age-related macular degeneration; Lewy body disease
  • No development reported Parkinson's disease
  • Discontinued Cognition disorders

Most Recent Events

  • 26 Mar 2026 Cognition Therapeutics plans a meeting with FDA Division of Psychiatry for registrational plan in Lewy body disease by mid-2026
  • 28 Feb 2026 No recent reports of development identified for preclinical development in Parkinson's-disease in USA (PO)
  • 27 Jan 2026 Cognition Therapeutics completes Type C meeting with FDA for the phase-IIb trial in Lewy bodies disease (DLB)

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