OPT 302

Drug Profile

OPT 302

Alternative Names: OPT-302; soluble VEGFR-3; VGX 300

Latest Information Update: 29 Mar 2018

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At a glance

  • Originator Vegenics
  • Developer Opthea
  • Class Eye disorder therapies
  • Mechanism of Action Vascular endothelial growth factor C inhibitors; Vascular endothelial growth factor D inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Wet age-related macular degeneration
  • Phase I/II Diabetic macular oedema

Most Recent Events

  • 03 Jan 2018 Phase-I/II clinical trials in Diabetic macular oedema (Combination therapy, Treatment-experienced) in Australia and USA (Intravitreous)
  • 06 Nov 2017 Phase-II clinical trials in Wet age-related macular degeneration (Combination therapy, Treatment naive) in USA (Intravitreous) (NCT03345082)
  • 15 Aug 2017 Updated efficacy data from a phase I/II trial in Wet age related macular degeneration released by Opthea
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