Drug Profile


Alternative Names: Neo Vax; NEO-PV-01; Neoantigen-based vaccine - Neon Therapeutics; NeoAntigen-peptides; Personalized-neoantigen-cancer-vaccine-Neon-Therapeutics

Latest Information Update: 23 Mar 2018

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At a glance

  • Originator Broad Institute; Dana-Farber Cancer Institute
  • Developer Bristol-Myers Squibb; Dana-Farber Cancer Institute; Merck Sharp & Dohme; Neon Therapeutics
  • Class Cancer vaccines; Peptide vaccines; Peptides
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Bladder cancer; Glioblastoma; Malignant melanoma; Non-small cell lung cancer

Most Recent Events

  • 01 Mar 2018 Phase-I clinical trials in Non-small cell lung cancer (Metastatic disease, Late-stage disease, Combination therapy, First-line therapy) in USA (Parenteral) (NCT03380871)
  • 14 Feb 2018 Washington University School of Medicine plans a phase I trial for Glioblastoma (Combination therapy, Newly diagnosed) in USA (NCT03422094)
  • 07 Dec 2017 Dana-Farber Cancer Institute plans a pilot phase I trial for Follicular lymphoma (Combination therapy, First-line therapy) in USA in December 2017 (NCT03361852)
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