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MEDI 4276

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Drug Profile

MEDI 4276

Alternative Names: MEDI4276

Latest Information Update: 31 Oct 2021

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At a glance

  • Originator MedImmune
  • Class Antineoplastics; Bispecific antibodies; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action ERBB 2 receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Breast cancer; Gastric cancer

Most Recent Events

  • 01 Aug 2018 Discontinued - Phase-I for Breast cancer (Late-stage disease, Second-line therapy or greater, In adults) in USA (PO) (AstraZeneca pipeline, July 2018)
  • 01 Aug 2018 Discontinued - Phase-I for Gastric cancer (Late-stage disease, Second-line therapy or greater, In adults) in USA (PO) (AstraZeneca pipeline, July 2018)
  • 05 Mar 2018 Adverse events, efficacy and pharmacokinetics data from a phase I trial in Cancer presented at the 16th International Congress on Targeted Anticancer Therapies (TAT-2018)

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