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Anti-glypican 3 chimeric antigen receptor T cell therapy - CARSgen

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Drug Profile

Anti-glypican 3 chimeric antigen receptor T cell therapy - CARSgen

Alternative Names: Anti glypican 3 chimeric antigen receptor T cell therapy - CARSgen; anti-GPC3 CAR T; Anti-GPC3 chimeric antigen receptor T cell therapy – CARsgen; CAR-GPC3 T-cell; CT-011 - CARSgen; Glypican-3-chimeric-antigen-receptor-T-cell-therapy; GPC3-CAR-T cell therapy - CARSgen; GPC3-CAR/CSG-GPC3

Latest Information Update: 28 Oct 2024

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At a glance

  • Originator CARsgen
  • Developer CARsgen; Shanghai Jiao Tong University
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Liver cancer
  • No development reported Breast cancer; Gastric cancer; Lung cancer

Most Recent Events

  • 28 Oct 2024 No recent reports of development identified for phase-I development in Liver-cancer(In the elderly, Late-stage disease, Second-line therapy or greater, In adults) in China (IV, Infusion)
  • 15 Jan 2024 CARsgen plans clinical trial for Liver cancer in China
  • 15 Jan 2024 National Medical Products Administration (NMPA), China approves IND application for Anti-glypican 3 chimeric antigen receptor T cell therapy in Liver cancer

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