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Resiniferatoxin - Grunenthal

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Drug Profile

Resiniferatoxin - Grunenthal

Alternative Names: Lopain; MTX-071; RTX - Grunenthal; RTX-GRT7039

Latest Information Update: 05 Feb 2026

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At a glance

  • Originator Mestex AG
  • Developer Grunenthal
  • Class Acetates; Analgesics; Anti-inflammatories; Azulenes; Non-opioid analgesics; Phenols; Phenyl ethers; Small molecules
  • Mechanism of Action TRPV1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Musculoskeletal pain

Most Recent Events

  • 05 Feb 2026 Discontinued - Phase-I/II for Musculoskeletal pain (In the elderly, In adults) in Belgium (Intra-articular)
  • 05 Feb 2026 Discontinued - Phase-II for Musculoskeletal pain (In adults, In the elderly) in Slovakia (Intra-articular)
  • 05 Feb 2026 Discontinued - Phase-II for Musculoskeletal pain (In the elderly, In adults) in Croatia (Intra-articular)

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