Drug Profile


Alternative Names: Anti-CEA CAR-T; Anti-CEA T-cells; CAR-T CEA; CAR-T-CEA-therapy; CEA CART; Designer T-cells

Latest Information Update: 03 Apr 2018

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At a glance

  • Originator BDL Products, Inc.; CARgenix Holdings LLC
  • Developer Roger Williams Medical Center
  • Class CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Liver metastases

Most Recent Events

  • 03 Apr 2018 Phase-I development is ongoing in Liver metastases(Inoperable/Unresectable, Second-line therapy or greater) in USA (Intrahepatic, Infusion)
  • 05 Mar 2018 Initial efficacy and adverse events data from a phase Ib HITM-SURE trial in Liver metastases released by Sorrento Therapeutics
  • 05 Mar 2018 Sorrento Therapeutics plans a clinical trial for Cancer (Combination therapy) in the second half of 2018
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