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Ranibizumab biosimilar - Xbrane

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Drug Profile

Ranibizumab biosimilar - Xbrane

Alternative Names: Lucamzi; Lucentis biosimilar - Xbrane; Ximluci; Xlucane

Latest Information Update: 07 Apr 2025

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At a glance

  • Originator Xbrane
  • Class Eye disorder therapies; Immunoglobulin fragments; Monoclonal antibodies
  • Mechanism of Action Vascular endothelial growth factor A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Choroidal neovascularisation; Diabetic macular oedema; Diabetic retinopathy; Retinal vein occlusion; Wet age-related macular degeneration
  • Preregistration Degenerative myopia; Retinal oedema

Most Recent Events

  • 20 Mar 2025 Xbrane plans to launch Ximluci in the US together with partner Valorum during 2026
  • 31 Dec 2024 Xbrane re-submittes the BLA to the US FDA for the treatment of Retinal disorders
  • 08 Jul 2024 Xbrane plans to re-submit the BLA to the US FDA for treatment of retinal disorders in the fourth quarter of 2024

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