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Olacaftor - Vertex Pharmaceuticals

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Drug Profile

Olacaftor - Vertex Pharmaceuticals

Alternative Names: VX-440

Latest Information Update: 11 Oct 2021

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At a glance

  • Originator Vertex Pharmaceuticals
  • Class Pyridines; Pyrrolidines
  • Mechanism of Action Cystic fibrosis transmembrane conductance regulator stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Cystic fibrosis

Most Recent Events

  • 11 Oct 2021 Discontinued - Phase-I for Cystic fibrosis (Monotherapy, In volunteers) in USA (PO) before October 2021 (Vertex Pharmaceuticals pipeline, October 2021)
  • 11 Oct 2021 Discontinued - Phase-II for Cystic fibrosis (Combination therapy) in USA, Austria, Australia, Belgium, Belgium, Canada, Denmark, Germany, Italy, United Kingdom, Spain, Spain, Netherlands (PO) before October 2021 (Vertex Pharmaceuticals pipeline, October 2021)
  • 28 Feb 2019 No recent reports of development identified for phase-I development in Cystic-fibrosis(Monotherapy, In volunteers) in USA (PO)

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