MRG 201

Drug Profile

MRG 201

Alternative Names: miR-29 replacement; MRG-201

Latest Information Update: 14 Sep 2017

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At a glance

  • Originator University of Texas Southwestern Medical Center
  • Developer miRagen Therapeutics; Yale University
  • Class Antifibrotics; MicroRNAs; Skin disorder therapies
  • Mechanism of Action Collagen inhibitors; RNA inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Fibrosis
  • Preclinical Pulmonary fibrosis

Most Recent Events

  • 11 Sep 2017 Pharmacodynamics data from a preclinical trial in Pulmonnary fibrosis presented at the European Respiratory Society International Congress (ERS-2017)
  • 01 Sep 2017 Preclinical trials in Pulmonary fibrosis in USA (Inhalation) before September 2017
  • 11 Aug 2017 miRagen Therapeutics plans a phase IIa trial for Fibrosis in patients with a predisposition for keloid formation in the second quarter of 2018
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