JCAR 020

Drug Profile

JCAR 020

Alternative Names: Anti MUC-16 chimeric antigen receptor T-cell therapy; Anti-MUC16 CAR-T cell therapy-Juno; IL-12-secreting MUC-16 CAR-T cell therapy; JCAR020; MUC-16-IL-12 armored CAR-T-cells; MUC-16-IL-12-armored chimeric antigen receptor T-cells

Latest Information Update: 13 Apr 2018

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At a glance

  • Originator Memorial Sloan-Kettering Cancer Center
  • Developer Juno Therapeutics
  • Class Antineoplastics; CAR-T cell therapies; T lymphocyte cell therapies
  • Mechanism of Action T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Ovarian cancer

Most Recent Events

  • 13 Apr 2018 JCAR 020 is still in phase I trials for Ovarian cancer in USA
  • 06 Mar 2018 Juno Therapeutics has been acquired by Celgene Corporation
  • 28 Feb 2018 No recent reports of development identified for phase-I development in Ovarian-cancer in USA (Parenteral)
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