Milvexian - Bristol-Myers Squibb/Johnson & Johnson Innovative Medicine
Alternative Names: BMS 177; BMS-986177; JNJ-3093; JNJ-70033093Latest Information Update: 21 Jan 2025
At a glance
- Originator Bristol-Myers Squibb
- Developer Bristol-Myers Squibb; Johnson & Johnson Innovative Medicine
- Class Antiarrhythmics; Antithrombotics; Aza compounds; Cardiovascular therapies; Chlorobenzenes; Fluorine compounds; Macrocyclic compounds; Pyrimidinones; Small molecules; Triazoles; Vascular disorder therapies
- Mechanism of Action Factor XIa inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase III Acute coronary syndromes; Atrial fibrillation; Stroke
- Discontinued Venous thromboembolism
Most Recent Events
- 08 Sep 2024 Pharmacokinetics, pharmacodynamics and adverse event data from a phase I trial in healthy volunteers presented at the American College of Clinical Pharmacology Annual Meeting (ACCP-2024)
- 30 Aug 2024 Pharmacokinetics and pharmacodynamics data from the AXIOMATIC-TKR phase II trial in Venous thromboembolism presented at the annual congress of the European Society of Cardiology (ESC-Card-2024)
- 28 Aug 2024 No recent reports of development identified for phase-I development in Stroke(In volunteers) in United Kingdom (PO, Liquid)