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Avexitide - Amylyx Pharmaceuticals

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Drug Profile

Avexitide - Amylyx Pharmaceuticals

Alternative Names: Avexitide acetate; Exendin (9-39)amide; Exendin 9; Exendin 9-39 acetate; Exendin-(9-39); Exendin-9,39

Latest Information Update: 28 Aug 2025

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At a glance

  • Originator Stanford University
  • Developer Cambridge University Hospitals; Eiger BioPharmaceuticals, Inc.; Stanford University
  • Class Antihypoglycaemics; Peptide fragments
  • Mechanism of Action Glucagon-like peptide-1 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hypoglycaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Congenital hyperinsulinism; Hypoglycaemia

Most Recent Events

  • 08 Aug 2025 Efficacy, adverse event and pharmacodynamic data from a phase II trial in Hypoglycaemia released by Amylyx Pharmaceuticals
  • 15 May 2025 Mayo Clinic in collaboration with Amylyx Pharmaceuticals plans a phase-II trial (In volunteers) in USA (IV, Infusion), (NCT06972407)
  • 12 Mar 2025 Amylyx Pharmaceuticals plans a clinical trial for Kidney disorders in Denmark in May 2025 (IV) (NCT06872060)

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