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Research programme: epigenetic cancer therapies - H. Lee Moffitt Cancer Center and Research Institute

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Drug Profile

Research programme: epigenetic cancer therapies - H. Lee Moffitt Cancer Center and Research Institute

Alternative Names: MA2 014; MA2-1014

Latest Information Update: 20 Mar 2019

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At a glance

  • Originator H. Lee Moffitt Cancer Center and Research Institute
  • Class Antineoplastics; Small molecules
  • Mechanism of Action BRD4 protein inhibitors; Janus kinase 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Haematological malignancies; Myeloproliferative disorders; Solid tumours

Most Recent Events

  • 03 Dec 2015 Pharmacodynamics data from a preclinical trial in Myeloproliferative disorders released by Aptose Biosciences
  • 01 Dec 2015 Preclinical trials in Myeloproliferative disorders in USA (unspecified route) before December 2015
  • 10 Nov 2015 Preclinical trials in Haematological malignancies in USA (unspecified route)

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