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Fosmanogepix - Basilea Pharmaceutica

Drug Profile

Fosmanogepix - Basilea Pharmaceutica

Alternative Names: APX-001; E-1211; E-210; PF-07842805

Latest Information Update: 31 May 2024

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At a glance

  • Originator Eisai Co Ltd
  • Developer Amplyx Pharmaceuticals
  • Class Aminopyridines; Antifungals; Antineoplastics; Oxazoles; Phosphates; Small molecules
  • Mechanism of Action GWT1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Coccidioidomycosis; Mycoses; Candidiasis; Cryptococcosis; Aspergillosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Aspergillosis; Candidaemia
  • No development reported Acute myeloid leukaemia; Coccidioidomycosis; Mycoses

Most Recent Events

  • 29 May 2024 Basilea Pharmaceutica initiates an expanded access programme to fosmanogepix for Invasive fungal infections (PO, tablets) (IV, Infusion) (NCT06433128)
  • 28 Apr 2024 No recent reports of development identified for phase-I development in Mycoses(In volunteers) in USA (PO)
  • 05 Jan 2024 Basilea Pharmaceutica plans a phase III trial for invasive mold infections by end of 2024
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