AF 130

Drug Profile

AF 130

Alternative Names: AF-130

Latest Information Update: 03 Jan 2017

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At a glance

  • Originator Roche
  • Developer Merck & Co
  • Class Analgesics; Antihypertensives; Heart failure therapies; Small molecules
  • Mechanism of Action Purinergic P2X3 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Hypertension; Migraine

Most Recent Events

  • 18 May 2016 Afferent Pharmaceuticals completes a phase I trial in healthy volunteers in USA (NCT02652936)
  • 18 May 2016 Afferent Pharmaceuticals plans a phase II trial for Hypertension in USA
  • 08 Dec 2015 Phase-I clinical trials in Hypertension in United Kingdom (PO) (NCT02652936)
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